wqspt: Permutation Test for Weighted Quantile Sum Regression
Implements a permutation test method for the weighted quantile sum (WQS) regression, building off the 'gWQS' package (Renzetti et al. <https://CRAN.R-project.org/package=gWQS>). Weighted quantile sum regression is a statistical technique to evaluate the effect of complex exposure mixtures on an outcome (Carrico et al. 2015 <doi:10.1007/s13253-014-0180-3>). The model features a statistical power and Type I error (i.e., false positive) rate trade-off, as there is a machine learning step to determine the weights that optimize the linear model fit. This package provides an alternative method based on a permutation test that should reliably allow for both high power and low false positive rate when utilizing WQS regression (Day et al. 2022 <doi:10.1289/EHP10570>).
| Version: | 1.0.2 | 
| Depends: | R (≥ 3.5.0) | 
| Imports: | rlang, gWQS, pbapply, ggplot2, mvtnorm, viridis, extraDistr, cowplot, methods, MASS, car, future, future.apply, pscl, reshape2, nnet | 
| Suggests: | rmarkdown, knitr, testthat (≥ 3.0.0) | 
| Published: | 2025-03-05 | 
| DOI: | 10.32614/CRAN.package.wqspt | 
| Author: | Drew Day [aut, cre],
  James Peng [aut],
  Adam Szpiro [aut] | 
| Maintainer: | Drew Day  <dday612 at gmail.com> | 
| License: | GPL-3 | 
| NeedsCompilation: | no | 
| Materials: | README, NEWS | 
| CRAN checks: | wqspt results | 
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